Ik had onlangs dit probleem:
ImproperlyConfigured: Error loading psycopg2 module: No module named _psycopg
... en dit commando was het antwoord:
sudo apt-get install libapache2-mod-wsgi-py3
Referentie:
http://python.6.x6.nabble.com/ImproperlyConfigured-Error-loading-psycopg2-module-No-module-named-psycopg-td5044145.html